Steger-Hartmann, T.: search on Z-Library

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1

A big data approach to the concordance of the toxicity of pharmaceuticals in animals and humans

Clark, Matthew, Steger-Hartmann, Thomas

Journal:

Regulatory Toxicology and Pharmacology

Year:

2018

Language:

english

File:

PDF, 3.84 MB

english, 2018

2

Translating in vitro to in vivo and animal to human

Steger-Hartmann, T., Raschke, M.

Journal:

Current Opinion in Toxicology

Year:

2020

Language:

english

File:

PDF, 995 KB

english, 2020

3

Making reliable negative predictions of human skin sensitisation using an in silico fragmentation approach

Chilton, Martyn L., Macmillan, Donna S., Steger-Hartmann, Thomas, Hillegass, Jedd, Bellion, Phillip, Vuorinen, Anna, Etter, Sylvain, Smith, Benjamin P.C., White, Angela, Sterchele, Paul, De Smedt, Ann

Journal:

Regulatory Toxicology and Pharmacology

Year:

2018

Language:

english

File:

PDF, 1.09 MB

english, 2018

4

[Ernst Schering Foundation Symposium Proceedings] Oncogenes Meet Metabolism Volume 2007/4 || Use of Metabolic Pathway Flux Information in Anticancer Drug Design

Kroemer, G., Mumberg, D., Keun, H., Riefke, B., Steger-Hartmann, T., Petersen, K.

Year:

2008

Language:

english

File:

PDF, 283 KB

english, 2008

5

A quantitative in silico model for predicting skin sensitization using a nearest neighbours approach within expert-derived structure-activity alert spaces

Canipa, Steven J., Chilton, Martyn L., Hemingway, Rachel, Macmillan, Donna S., Myden, Alun, Plante, Jeffrey P., Tennant, Rachael E., Vessey, Jonathan D., Steger-Hartmann, Thomas, Gould, Janet, Hillega

Journal:

Journal of Applied Toxicology

Year:

2017

Language:

english

File:

PDF, 775 KB

english, 2017

6

Guest Editorial: Advances in Computational Toxicology

Steger-Hartmann, Thomas

Journal:

Molecular Informatics

Year:

2013

Language:

english

File:

PDF, 110 KB

english, 2013

7

[Ernst Schering Foundation Symposium Proceedings] Oncogenes Meet Metabolism Volume 2007/4 || Role of the Metabolic Stress Responses of Apoptosis and Autophagy in Tumor Suppression

Kroemer, G., Mumberg, D., Keun, H., Riefke, B., Steger-Hartmann, T., Petersen, K.

Year:

2008

Language:

english

File:

PDF, 220 KB

english, 2008

8

Green Toxicology: a strategy for sustainable chemical and material development

Crawford, Sarah E., Hartung, Thomas, Hollert, Henner, Mathes, Björn, van Ravenzwaay, Bennard, Steger-Hartmann, Thomas, Studer, Christoph, Krug, Harald F.

Journal:

Environmental Sciences Europe

Year:

2017

Language:

english

File:

PDF, 1.54 MB

english, 2017

9

Evaluating the role of zinc in the occurrence of fibrosis of the skin: A preclinical study

Hubertus Pietsch, Christiane Pering, Philipp Lengsfeld, Jakob Walter, Thomas Steger-Hartmann, Sven Golfier, Thomas Frenzel, Joachim Hütter, Hans-Joachim Weinmann, Martin A. Sieber

Journal:

Journal of Magnetic Resonance Imaging

Year:

2009

Language:

english

File:

PDF, 4.00 MB

english, 2009

10

Biological Degradation of Cyclophosphamide and Its Occurrence in Sewage Water

T. Steger-Hartmann, K. Kümmerer, A. Hartmann

Journal:

Ecotoxicology and Environmental Safety

Year:

1997

Language:

english

File:

PDF, 141 KB

english, 1997

11

Induced Accumulation and Potential Antioxidative Function of Rutin in Two Cultivars of Nicotiana tabacum L.

Steger-Hartmann, Thomas, Koch, Ulrich, Dunz, Thomas, Wagner, Edgar

Journal:

Zeitschrift für Naturforschung C

Year:

1994

Language:

english

File:

PDF, 5.88 MB

english, 1994

12

Gadolinium-based contrast agents and NSF: Evidence from animal experience

Martin A. Sieber, Thomas Steger-Hartmann, Philipp Lengsfeld, Hubertus Pietsch

Journal:

Journal of Magnetic Resonance Imaging

Year:

2009

Language:

english

File:

PDF, 927 KB

english, 2009

13

In silico prediction of in vivo toxicity - the first steps of the e-Tox consortium

T. Steger-Hartmann, F. Pognan, F. Sanz, C. Diaz, A. Sutter, M. Pastor

Journal:

Toxicology Letters

Year:

2010

Language:

english

File:

PDF, 89 KB

english, 2010

14

The Future of Stem Cells and Toxicity Screening

Parker, Moderator: Graham C., Trosko, Participants: James E., Steger-Hartmann, Thomas, Young, Bruce K.

Journal:

Applied In Vitro Toxicology

Year:

2017

Language:

english

File:

PDF, 117 KB

english, 2017

15

Incorporation of in silico biodegradability screening in early drug development—a feasible approach?

Thomas Steger-Hartmann, Reinhard Länge, Klaus Heuck

Journal:

Environmental Science and Pollution Research

Year:

2011

Language:

english

File:

PDF, 787 KB

english, 2011

16

Morphological sex reversal upon short-term exposure to endocrine modulators in juvenile fathead minnow (Pimephales promelas)

Melanie Zerulla, R Länge, T Steger-Hartmann, G Panter, T Hutchinson, D.R Dietrich

Journal:

Toxicology Letters

Year:

2002

Language:

english

File:

PDF, 276 KB

english, 2002

17

Panel discussion: The Innovative Medicines Initiative (IMI) – high hopes and first experiences

Thomas Steger-Hartmann, Friedlieb Pfannkuch

Journal:

Toxicology Letters

Year:

2009

Language:

english

File:

PDF, 40 KB

english, 2009

18

Human risk assessment of drinking water residues from pharmaceuticals: environmental pathways, pharmacological potency and toxicity

Länge, Reinhard, Steger-Hartmann, Thomas

Journal:

Toxicology Letters

Year:

2013

Language:

english

File:

PDF, 63 KB

english, 2013

19

Discussion by Reinhard Länge et al. on “Degradation of the endocrine disrupting chemicals (EDCs) carbamazepine, clofibric acid, and iopromide by corona discharge over water” by Krause et al. [Chemosphere 75(2) (2009) 163–168]

Reinhard Länge, Thomas Steger-Hartmann, Steffen A. Borden, Hubertus Pietsch

Journal:

Year:

2010

Language:

english

File:

PDF, 141 KB

english, 2010

20

Biodegradability of the anti-tumour agent ifosfamide and its occurrence in hospital effluents and communal sewage

Klaus Kümmerer, Thomas Steger-Hartmann, Michael Meyer

Journal:

Year:

1997

Language:

english

File:

PDF, 522 KB

english, 1997

21

A benchmark data set for in silico prediction of ames mutagenicity

K Hansen, S Mika, T Schroeter, A Sutter, A Ter Laak, T Steger-Hartmann, N Heinrich, K-R Müller

Journal:

Chemistry Central Journal

Year:

2009

Language:

english

File:

PDF, 62 KB

english, 2009

22

Effects of synthetic gestagens on fish reproduction

Jana Zeilinger, Thomas Steger-Hartmann, Edmund Maser, Stephan Goller, Richardus Vonk, Reinhard Länge

Journal:

Environmental Toxicology and Chemistry

Year:

2009

Language:

english

File:

PDF, 4.66 MB

english, 2009

23

Towards the creation of an international toxicology information centre

Philip N. Judson, Paul A. Cooke, Nancy G. Doerrer, Nigel Greene, Robert P. Hanzlik, Christopher Hardy, Andreas Hartmann, David Hinchliffe, Julie Holder, Lutz Müller, Thomas Steger-Hartmann, Andreas Ro

Journal:

Year:

2005

Language:

english

File:

PDF, 467 KB

english, 2005

24

[Journal of Chromatography Library] Protein Liquid Chromatography Volume 61 || Chromatography Software

Steger-Hartmann, Thomas

Year:

2000

Language:

english

File:

PDF, 776 KB

english, 2000

25

[Ernst Schering Foundation Symposium Proceedings] Oncogenes Meet Metabolism Volume 2007/4 || Using Metabolomics to Monitor Anticancer Drugs

Kroemer, G., Mumberg, D., Keun, H., Riefke, B., Steger-Hartmann, T., Petersen, K.

Year:

2008

Language:

english

File:

PDF, 195 KB

english, 2008

26

Legacy data sharing to improve drug safety assessment: the eTOX project

Sanz, Ferran, Pognan, François, Steger-Hartmann, Thomas, Díaz, Carlos, Cases, Montserrat, Pastor, Manuel, Marc, Philippe, Wichard, Joerg, Briggs, Katharine, Watson, David K., Kleinöder, Thomas, Yang,

Journal:

Nature Reviews Drug Discovery

Year:

2017

Language:

english

File:

PDF, 118 KB

english, 2017

27

Use of computer-assisted prediction of toxic effects of chemical substances

Brigitte Simon-Hettich, Andreas Rothfuss, Thomas Steger-Hartmann

Journal:

Year:

2006

Language:

english

File:

PDF, 118 KB

english, 2006

28

Benchmark Data Set for in Silico Prediction of Ames Mutagenicity

Hansen, Katja, Mika, Sebastian, Schroeter, Timon, Sutter, Andreas, ter Laak, Antonius, Steger-Hartmann, Thomas, Heinrich, Nikolaus, Müller, Klaus-Robert

Journal:

Journal of Chemical Information and Modeling

Year:

2009

Language:

english

File:

PDF, 137 KB

english, 2009

29

A Review of Preclinical Safety Data for Magnevist (Gadopentetate Dimeglumine) in the Context of Nephrogenic Systemic Fibrosis

Steger-Hartmann, Thomas, Hofmeister, Rainer, Ernst, Rainer, Pietsch, Hubertus, Sieber, Martin A., Walter, Jacob

Journal:

Investigative Radiology

Year:

2010

Language:

english

File:

PDF, 481 KB

english, 2010

30

Setting the stage for next-generation risk assessment with non-animal approaches: the EU-ToxRisk project experience

MonÃ©, M. J., Pallocca, G., Escher, S. E., Exner, T., Herzler, M., Bennekou, S. Hougaard, Kamp, H., Kroese, E. D., Leist, Marcel, Steger-Hartmann, T., van de Water, B.

Journal:

Archives of Toxicology

Year:

2020

File:

PDF, 2.18 MB

2020

31

CMR2009: 5.06: Preclinical studies to investigate the role of renal impairment and to identify biomarkers in the pathology of NSF

M. A. Sieber, M. Raschke, M. Hecht, T. Steger-Hartmann, T. Frenzel, J. Hütter, H. Pietsch

Journal:

Contrast Media & Molecular Imaging

Year:

2009

Language:

english

File:

PDF, 95 KB

english, 2009

32

Investigations into the environmental fate and effects of iopromide (ultravist), a widely used iodinated X-ray contrast medium

Thomas Steger-Hartmann, Reinhard Länge, Hermann Schweinfurth, Matthias Tschampel, Irmgard Rehmann

Journal:

Year:

2002

Language:

english

File:

PDF, 214 KB

english, 2002

33

[Ernst Schering Foundation Symposium Proceedings] Oncogenes Meet Metabolism Volume 2007/4 || Molecular Imaging of Tumor Metabolism and Apoptosis

Kroemer, G., Mumberg, D., Keun, H., Riefke, B., Steger-Hartmann, T., Petersen, K.

Year:

2008

Language:

english

File:

PDF, 290 KB

english, 2008

34

Value of shared preclinical safety studies – The eTOX database

Briggs, Katharine, Barber, Chris, Cases, Montserrat, Marc, Philippe, Steger-Hartmann, Thomas

Journal:

Toxicology Reports

Year:

2015

Language:

english

File:

PDF, 2.07 MB

english, 2015

35

The IMI eTOX initiative – Data mining, read-across and predictive models for target evaluation and early drug candidate assessment

Steger-Hartmann, Thomas, Pognan, Francois, Sanz, Ferran

Journal:

Toxicology Letters

Year:

2017

Language:

english

File:

PDF, 84 KB

english, 2017

36

The involvement of pro-inflammatory cytokines in nephrogenic systemic fibrosis – A mechanistic hypothesis based on preclinical results from a rat model treated with gadodiamide

T. Steger-Hartmann, M. Raschke, B. Riefke, H. Pietsch, M.A. Sieber, J. Walter

Journal:

Experimental and Toxicologic Pathology

Year:

2009

Language:

english

File:

PDF, 1.20 MB

english, 2009

37

Preclinical Safety Assessment of Vasovist (Gadofosveset trisodium), a New Magnetic Resonance Imaging Contrast Agent for Angiography

Steger-Hartmann, Thomas, Graham, Philip B., M??ller, Simone, Schweinfurth, Hermann

Journal:

Investigative Radiology

Year:

2006

Language:

english

File:

PDF, 1.23 MB

english, 2006

38

Impact of Renal Impairment on Long-Term Retention of Gadolinium in the Rodent Skin Following the Administration of Gadolinium-Based Contrast Agents

Pietsch, Hubertus, Lengsfeld, Philipp, Steger-Hartmann, Thomas, Löwe, Andrea, Frenzel, Thomas, Hütter, Joachim, Sieber, Martin A.

Journal:

Investigative Radiology

Year:

2009

Language:

english

File:

PDF, 1.81 MB

english, 2009

39

Induced Accumulation and Potential Antioxidative Function of Rutin in Two Cultivars of Nicotiana tabacum L.

Steger-Hartmann, Thomas, Koch, Ulrich, Dunz, Thomas, Wagner, Edgar

Journal:

Zeitschrift für Naturforschung C

Year:

1994

File:

PDF, 5.88 MB

1994

40

[Ernst Schering Foundation Symposium Proceedings] Oncogenes Meet Metabolism Volume 2007/4 || Pyruvate Kinase Type M2: A Key Regulator Within the Tumour Metabolome and a Tool for Metabolic Profiling of Tumours

Kroemer, G., Mumberg, D., Keun, H., Riefke, B., Steger-Hartmann, T., Petersen, K.

Year:

2008

Language:

english

File:

PDF, 758 KB

english, 2008

41

[Ernst Schering Foundation Symposium Proceedings] Oncogenes Meet Metabolism Volume 2007/4 || The Interplay Between MYC and HIF in the Warburg Effect

Kroemer, G., Mumberg, D., Keun, H., Riefke, B., Steger-Hartmann, T., Petersen, K.

Year:

2008

Language:

english

File:

PDF, 239 KB

english, 2008

42

[Ernst Schering Foundation Symposium Proceedings] Oncogenes Meet Metabolism Volume 2007/4 || Biomarker Discovery for Drug Development and Translational Medicine Using Metabonomics

Kroemer, G., Mumberg, D., Keun, H., Riefke, B., Steger-Hartmann, T., Petersen, K.

Year:

2008

Language:

english

File:

PDF, 272 KB

english, 2008

43

Toxicological Safety Evaluation of Gadobutrol

Wack, Christiane, Steger-Hartmann, Thomas, Mylecraine, Louis, Hofmeister, Rainer

Journal:

Investigative Radiology

Year:

2012

Language:

english

File:

PDF, 243 KB

english, 2012

44

[Ernst Schering Foundation Symposium Proceedings] Oncogenes Meet Metabolism Volume 2007/4 || Cancer Diagnostics Using 1H-NMR-Based Metabonomics

Kroemer, G., Mumberg, D., Keun, H., Riefke, B., Steger-Hartmann, T., Petersen, K.

Year:

2008

Language:

english

File:

PDF, 228 KB

english, 2008

45

Vorkommen natürlicher und synthetischer östrogener Steroide in Wässern des süd- und mitteldeutschen Raumes

Peter Adler, Thomas Steger-Hartmann, Wolfgang Kalbfus

Journal:

CLEAN – Soil, Air, Water

Year:

2001

Language:

german

File:

PDF, 1.16 MB

german, 2001

46

Der Leitfähigkeitstest — Ein Testsystem zur Ermittlung der membrantoxischen Eigenschaften von Substanzen

H. Dürholt, Dipl.-Biol. T. Steger-Hartmann, J. Eich, Prof. Dr. E. Wagner

Journal:

CLEAN – Soil, Air, Water

Year:

1995

File:

PDF, 483 KB

1995

47

Specific Detection of Membrane-Toxic Substances with a Conductivity Assay

J. Eich, H. Dürholt, T. Steger-Hartmann, E. Wagner

Journal:

Ecotoxicology and Environmental Safety

Year:

2000

Language:

english

File:

PDF, 549 KB

english, 2000

48

[Ernst Schering Foundation Symposium Proceedings] Oncogenes Meet Metabolism Volume 2007/4 || Human Metabolic Phenotyping and Metabolome Wide Association Studies

Kroemer, G., Mumberg, D., Keun, H., Riefke, B., Steger-Hartmann, T., Petersen, K.

Year:

2008

Language:

english

File:

PDF, 360 KB

english, 2008

49

In silico prediction of in vivo toxicities (eTox)—The Innovative Medicines Initiative Approach

Thomas Steger-Hartmann, Francois Pognan, Ferran Sanz, Carlos Acedo Diaz

Journal:

Toxicology Letters

Year:

2009

Language:

english

File:

PDF, 83 KB

english, 2009

50

Computational Prediction of the Chromosome-Damaging Potential of Chemicals

Rothfuss, Andreas, Steger-Hartmann, Thomas, Heinrich, Nikolaus, Wichard, Jörg

Journal:

Chemical Research in Toxicology

Year:

2006

Language:

english

File:

PDF, 83 KB

english, 2006

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